Higher Scientific Officer - Structural Biology of Cell Signalling

Salary Range: £37,050 - £45,732 per annum

Contract: Fixed term

External Advertising End Date: 22nd of September 2024

Key Information

Salary: Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here .

Duration of Contract: Fixed term contract for three years with possibility of extension

Hours per week: 35 hours per week (Full Time)

Under the leadership of Prof. Sebastian Guettler, we are seeking to appoint a Higher Scientific Officer to join the Structural Biology of Cell Signalling Team to investigate the molecular mechanisms of Wnt/beta-catenin signalling and telomere maintenance by in vitro approaches, with a particular focus on the regulation by ADP-ribosylation through tankyrase. The role consists of 70% research and 30% laboratory management responsibilities.

Key Requirements

The successful candidate must have skills and experience in biochemistry, biophysics, and/or structural biology, either X-ray crystallography or cryo-electron microscopy, to biological questions. The available projects will offer a stimulating balance of independence and collaboration. A large part of the work will be centred on understanding tankyrase regulation and modulation by small molecules.

About The Institute of Cancer Research

Why work for us? As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here .

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

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THE INSTITUTE OF CANCER RESEARCH

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Higher Scientific Officer - Structural Biology of Cell Signalling